Research of the Institute of Biomedicine and Translational Medicine

Read more about of the Department of Pharmacology.

Project: Mitochondrial dysfunction in axonal damage (Estonian Research Council, GMVBS0400PR)
Period: 01.01.2019−31.12.2023
Contact: Professor Allen Kaasik
E-mail: allen.kaasik@ut.ee

Project: Unraveling the molecular mechanisms underlying Ca2+-signaling modulation by CISD2, a wolfram syndrome-associated gene, and its interplay with Bcl-2 (Flemish Research Council, MMVBS21348)
Period: 01.01.2021−31.12.2024
Contact: Professor Allen Kaasik
E-mail: allen.kaasik@ut.ee

Project: Exploration of the therapeutic potential of the active vitamin D analogues: focus on the mood disorders and obesity (Estonian Research Council, GMVBS20080PR)
Period: 01.01.2010−31.12.2024
Contact: Professor Aleksandr Žarkovski
E-mail: aleksandr.zarkovski@ut.ee

Project: Development of curricula via international collaboration (Educational and Youth Board, DMVBS19558)
Period: 15.10.2019−14.10.2023
Contact: Associate Professor Miriam Ann Hickey
E-mail: miriam.ann.hickey@ut.ee

Project: The effect of DNA methyltransferase-inhibitor treatment on aberrant DNA methylation in human leukocytes: A novel pharmacological strategy for treatment of psychostimulant-induced drug addiction (Estonian Research Council, GMVBS22063PR)
Period: 01.01.2022−31.12.2026
Contact: Professor Anti Kalda
E-mail: anti.kalda@ut.ee

Read more about of the Department of Physiology.

Project: Potential biomarkers for the diagnosis, prognosis, and evaluation of treatment impact for first episode psychosis and schizophrenia spectrum disorders: translational approach (Estonian Research Council, GMVBS20067PR)
Period: 01.01.2020−31.12.2024
Contact: Professor Eero Vasar
E-mail: eero.vasar@ut.ee

Project: Endocannabinoid system as a possible modulator of psychiatric effects of the adhesion molecule Negr1 (Estonian Research Council, SMVBS22511)
Period: 01.12.2022−30.11.2024
Contact: Associate Professor Este Leidmaa
E-mail: este.leidmaa@ut.ee

The research projects of the Department of Biomedicine 

Read more about the research of the Molecular Pathology Research Group.

Project: Central immune tolerance (Estonian Research Council, GMVBS0377PR)
Period: 01.01.2019−31.12.2023
Contact: Professor Pärt Peterson  
E-mail: part.peterson@ut.ee

Project: Type I interferons and their autoantibodies in autoimmunity and COVID-19 (Estonian Research Council, GMVBS21081PR) 
Period: 01.01.2021−31.12.2025
Contact: Professor Kai Kisand
E-mail: kai.kisand@ut.ee

Project: Thymic Abnormalities in Rare Immunological Diseases (Ministry of Social Affairs, SMVBS20416) 
Period: 01.09.2020−31.08.2023
Contact: Professor Pärt Peterson
E-mail: part.peterson@ut.ee

Project: European Network Linking Informatics and Genomics of Helper T cells in Tissues (European Commission Horizon2020, MSCA Enlighten+, MMVBS21006R)
Period: 01.03.2021−28.02.2025
Contact: Professor Pärt Peterson 
E-mail: part.peterson@ut.ee

Project: Molecular mechanisms underlying impaired antiviral cytotoxic T cell responses in old age (Estonian Research Council, SMVBS21533)
Period: 01.12.2021−30.11.2023
Contact: Research Fellow Maarja Laos 
E-mail: maarja.laos@ut.ee

Project: Longitudinal study: immune responses following COVID-19 immunization and SARS-CoV-2 infection (Republic of Estonia Ministry of Education and Research, SMVPT21607T) 
Period: 01.10.2021−30.06.2023
Contact: professor Pärt Peterson 
E-mail: part.peterson@ut.ee

Project: The human genetic and immunological determinants of the clinical manifestations of SARS-CoV-2 infection: Towards personalised medicine (European Commission, MMVBS22163R)
Period: 01.06.2022−31.05.2026
Contact: Professor Kai Kisand
E-mail: kai.kisand@ut.ee

Read more about the research of the Laboratory of Precision and Nanomedicine.

Project: LDL-like nanoparticles for CAR-T-based glioblastoma immunotherapy (Estonian Research Council, SMVBS21620)
Period: 13.12.2021−12.12.2024
Contact: Professor Tambet Teesalu
E-mail: tambet.teesalu@ut.ee

Project: Reactivation of antitumor immune responses in gliomas using nanotechnology based targeted delivery (Estonian Research Council, SMVBS20627)
Period: 21.12.2020−31.12.2023
Contact: Professor Tambet Teesalu
E-mail: tambet.teesalu@ut.ee

Project: Peptide-targeted nanoparticles for delivery of therapeutics to tuberculosis (Bill and Melinda Gates Foundation, MMVBS21410)
Period: 07.04.2021−30.04.2025
Contact: Professor Tambet Teesalu
E-mail: tambet.teesalu@ut.ee

Project: Hemoglobin based Protein Nanocarriers for Tumour Oxygenation and a more effective Photodynamic Therapy (European Commission, MMVBS18435R)
Period: 01.03.2019−28.02.2023 
Contact: Professor Tambet Teesalu
E-mail: tambet.teesalu@ut.ee

Project: Precision targeting of infiltrative glioblastoma (Estonian Research Council, GMVBS23048PR)
Period: 01.01.2023−31.12.2027
Contact: Professor Tambet Teesalu
E-mail: tambet.teesalu@ut.ee

Read more about the research of the RNA Biology Research Group.

Project: Adjustment of tissue-specific immune responses in chronic inflammatory diseases by miRNAs (Estonian Research Council, GMVBS21063PR)
Period: 01.01.2021−31.12.2025
Contact: Professor Ana Rebane  
E-mail: ana.rebane@ut.ee

Project: Biomarkers in Atopic Dermatitis and Psoriasis (European Commission, Horizon2020, MMVBS19122)
Period: 01.01.2023−31.12.2027
Contact: Professor Ana Rebane  
E-mail: ana.rebane@ut.ee

Project: The role of microRNAs in the regulation of the generation and maintenance of skin resident memory T cells (Estonian Research Council, GMVBS22028J)
Period: 01.01.2022−31.12.2023
Contact: Research Fellow Helen Vaher 
E-mail: helen.vaher@ut.ee

Project: Precision targeting of infiltrative glioblastoma (Estonian Research Council, SMVBS22358)
Period: 01.09.2022−31.08.2024
Contact: Research Fellow Pavel Kudrin
E-mail: pavel.kudrin@ut.ee

Read more about the research of the Chair of Human Genetics.

Project: Mono- and digenic causes of male infertility in the exome sequencing era: novel genes, digenic inheritance, pleiotropic effects and clinical implications (Estonian Research Council, GMVBS21064PR)
Period: 01.01.2021–31.12.2025
Contact: Professor Maris Laan 
E-mail: maris.laan@ut.ee

Project: Maternal serum based multimarker test for the risk assessment to develop preeclampsia: translation to the clinic (ESTPRE study) (Estonian Research Council, SMVBS22077)
Period: 01.03.2022–31.05.2023
Contact: professor Maris Laan 
E-mail: maris.laan@ut.ee

Read more about the research of the Department of Immunology.

Project: Immune mechanisms in adulthood diabetes (Estonian Research Council, GMVBS0377PR)
Period: 01.01.2020–31.12.2024
Contact: Professor Raivo Uibo  
E-mail: raivo.uibo@ut.ee

Project: Human Exposomic Determinants of Immune Mediated Diseases (European Commission Horizon2020, MMVBS20017R)
Period: 01.01.2020–31.12.2024
Contact: professor Raivo Uibo  
E-mail: raivo.uibo@ut.ee

Read more about the research of the Department of Pathophysiology.

Project: Integrated model for personalized diabetic retinopathy screening and monitoring using risk-stratification and automated AI-based fundus image analysis (State Education Development Agency (SEDA), MMVBS21381)
Period: 01.05.2021–30.04.2024 
Contact: professor Vallo Volke  
E-mail: vallo.volke@ut.ee

Project: Staining study to – differentiate organelle originated EV´s from other nanoparticles – via f-NTA (Particle Metrix QUATT) (Particle Metrics GbmH, VMVBS21611)
Period: 28.10.2021–31.08.2023 
Contact: Professor Alireza Fazeli
E-mail: alireza.fazeli@ut.ee

Read more about the research of the Department of Anatomy.

Project: Human histology (Institute of the Estonian Language, DMVBS21510)
Period: 16.09.2021–01.09.2024
Contact: Associate Professor Marina Aunapuu
E-mail: marina.aunapuu@ut.ee

Read more about the research of the Department of Microbiology.

Project: conect4children- COllaborative Network for European Clinical Trials For Children (European Commission Horizon2020, MMVBS18106R)
Period: 01.05.2018–30.04.2024
Contact: Professor Irja Lutsar
E-mail: irja.lutsar@ut.ee

Project: Delivering a Unified Research Alliance of Biomedical and public health Laboratories against Epidemics (European Commission, MMVBS23022)
Period: 01.02.2023–31.01.2027
Contact: Professor Irja Lutsar
E-mail: irja.lutsar@ut.ee

Project: Boosting the One Health Research Excellence and Management Capacity of the Estonian University of Life Sciences (European Commission, MMVBS23128R)
Period: 01.01-2023–31.12.2025
Contact: Professor Irja Lutsar
E-mail: irja.lutsar@ut.ee

Project: SARS-coV2 variants Evaluation in pRegnancy and paeDIatrics cohorts (European Commission, MMVBS23269R)
Period: 01.05.2023–31.10.2025
Contact: Professor Irja Lutsar
E-mail: irja.lutsar@ut.ee

Project: GLP1 receptor agonist Liraglutide and NRF2 activator RTA-408 therapy to relieve neurodegenerative symptoms in rat model of Wolfram syndrome (Estonian Research Council, GMVBS20066PS)
Period: 01.01.2020–31.12.2023 
Contact: Associate Professor Mario Plaas
E-mail: mario.plaas@ut.ee

Project: Postnatal dysregulation of interneuron development in Wolfram Syndrome: A novel symptom and therapeutic target? (Estonian Research Council, SMVBS22510)
Period: 01.12.2022–30.11.2024 
Contact: Associate Professor Mario Plaas
E-mail: mario.plaas@ut.ee

Project: The Role of RNA-recognition Motif of NELFE in Brain Physiology (Estonian Research Council, GMVBS23135J)
Period: 01.03.2023–28.05.2025
Contact: Research Fellow Kadri Seppa
E-mail: kadri.seppa@ut.ee

Project: In vivo safety tests for probiotics (BioCC OÜ, LMVBS22224)
Period: 08.04.2022–31.12.2023
Contact: Associate Professor Mario Plaas
E-mail: mario.plaas@ut.ee

Project: Loss of Wfs1 affects the development and function of GABAergic pathways (TSF) (The Snow Foundation (TSF), MMVBS22562)
Period: 01.07.2022–31.12.2023
Contact: Associate Professor Mario Plaas
E-mail: mario.plaas@ut.ee

Project: Loss of Wfs1 affects the development and function of GABAergic pathways (Ellie White Foundation for Rare Genetic Disorders, MMVBS22534)
Period: 01.07.2022–30.06.2023
Contact: Associate Professor Mario Plaas
E-mail: mario.plaas@ut.ee