Research of the Institute of Biomedicine and Translational Medicine
The Institute of Biomedicine and Translational Medicine at the University of Tartu is a research and education institute in biomedical sciences. The research areas include basic and translational medicine.The mission is to create an internationally high standard research and education institute operating in the field of biomedicine.
The specific research projects are given at homepages of each work group:
Read more about of the Department of Pharmacology.
Project: Mitochondrial dysfunction in axonal damage (Estonian Research Council, GMVBS0400PR)
Period: 01.01.2019−31.12.2023
Contact: Professor Allen Kaasik
E-mail: allen.kaasik@ut.ee
Project: Unraveling the molecular mechanisms underlying Ca2+-signaling modulation by CISD2, a wolfram syndrome-associated gene, and its interplay with Bcl-2 (Flemish Research Council, MMVBS21348)
Period: 01.01.2021−31.12.2024
Contact: Professor Allen Kaasik
E-mail: allen.kaasik@ut.ee
Project: Exploration of the therapeutic potential of the active vitamin D analogues: focus on the mood disorders and obesity (Estonian Research Council, GMVBS20080PR)
Period: 01.01.2010−31.12.2024
Contact: Professor Aleksandr Žarkovski
E-mail: aleksandr.zarkovski@ut.ee
Project: The effect of DNA methyltransferase-inhibitor treatment on aberrant DNA methylation in human leukocytes: A novel pharmacological strategy for treatment of psychostimulant-induced drug addiction (Estonian Research Council, GMVBS22063PR)
Period: 01.01.2022−31.12.2026
Contact: Professor Anti Kalda
E-mail: anti.kalda@ut.ee
Read more about of the Department of Physiology.
Project: Potential biomarkers for the diagnosis, prognosis, and evaluation of treatment impact for first episode psychosis and schizophrenia spectrum disorders: translational approach (Estonian Research Council, GMVBS20067PR)
Period: 01.01.2020−31.12.2024
Contact: Professor Eero Vasar
E-mail: eero.vasar@ut.ee
Project: Endocannabinoid system as a possible modulator of psychiatric effects of the adhesion molecule Negr1 (Estonian Research Council, SMVBS22511)
Period: 01.12.2022−30.11.2024
Contact: Associate Professor Este Leidmaa
E-mail: este.leidmaa@ut.ee
The research projects of the Department of Biomedicine
Read more about the research of the Molecular Pathology Research Group.
Project: Central immune tolerance (Estonian Research Council, GMVBS0377PR)
Period: 01.01.2019−31.12.2023
Contact: Professor Pärt Peterson
E-mail: part.peterson@ut.ee
Project: Type I interferons and their autoantibodies in autoimmunity and COVID-19 (Estonian Research Council, GMVBS21081PR)
Period: 01.01.2021−31.12.2025
Contact: Professor Kai Kisand
E-mail: kai.kisand@ut.ee
Project: European Network Linking Informatics and Genomics of Helper T cells in Tissues (European Commission Horizon2020, MSCA Enlighten+, MMVBS21006R)
Period: 01.03.2021−28.02.2025
Contact: Professor Pärt Peterson
E-mail: part.peterson@ut.ee
Project: Molecular mechanisms underlying impaired antiviral cytotoxic T cell responses in old age (Estonian Research Council, SMVBS21533)
Period: 01.12.2021−30.11.2023
Contact: Research Fellow Maarja Laos
E-mail: maarja.laos@ut.ee
Project: The human genetic and immunological determinants of the clinical manifestations of SARS-CoV-2 infection: Towards personalised medicine (European Commission, MMVBS22163R)
Period: 01.06.2022−31.05.2026
Contact: Professor Kai Kisand
E-mail: kai.kisand@ut.ee
Read more about the research of the Laboratory of Precision and Nanomedicine.
Project: LDL-like nanoparticles for CAR-T-based glioblastoma immunotherapy (Estonian Research Council, SMVBS21620)
Period: 13.12.2021−12.12.2024
Contact: Professor Tambet Teesalu
E-mail: tambet.teesalu@ut.ee
Project: Reactivation of antitumor immune responses in gliomas using nanotechnology based targeted delivery (Estonian Research Council, SMVBS20627)
Period: 21.12.2020−31.12.2023
Contact: Professor Tambet Teesalu
E-mail: tambet.teesalu@ut.ee
Project: Peptide-targeted nanoparticles for delivery of therapeutics to tuberculosis (Bill and Melinda Gates Foundation, MMVBS21410)
Period: 07.04.2021−30.04.2025
Contact: Professor Tambet Teesalu
E-mail: tambet.teesalu@ut.ee
Project: Hemoglobin based Protein Nanocarriers for Tumour Oxygenation and a more effective Photodynamic Therapy (European Commission, MMVBS18435R)
Period: 01.03.2019−28.02.2023
Contact: Professor Tambet Teesalu
E-mail: tambet.teesalu@ut.ee
Project: Precision targeting of infiltrative glioblastoma (Estonian Research Council, GMVBS23048PR)
Period: 01.01.2023−31.12.2027
Contact: Professor Tambet Teesalu
E-mail: tambet.teesalu@ut.ee
Read more about the research of the RNA Biology Research Group.
Project: Adjustment of tissue-specific immune responses in chronic inflammatory diseases by miRNAs (Estonian Research Council, GMVBS21063PR)
Period: 01.01.2021−31.12.2025
Contact: Professor Ana Rebane
E-mail: ana.rebane@ut.ee
Project: Biomarkers in Atopic Dermatitis and Psoriasis (European Commission, Horizon2020, MMVBS19122)
Period: 01.01.2023−31.12.2027
Contact: Professor Ana Rebane
E-mail: ana.rebane@ut.ee
Project: The role of microRNAs in the regulation of the generation and maintenance of skin resident memory T cells (Estonian Research Council, GMVBS22028J)
Period: 01.01.2022−31.12.2023
Contact: Research Fellow Helen Vaher
E-mail: helen.vaher@ut.ee
Project: Precision targeting of infiltrative glioblastoma (Estonian Research Council, SMVBS22358)
Period: 01.09.2022−31.08.2024
Contact: Research Fellow Pavel Kudrin
E-mail: pavel.kudrin@ut.ee
Read more about the research of the Chair of Human Genetics.
Project: Mono- and digenic causes of male infertility in the exome sequencing era: novel genes, digenic inheritance, pleiotropic effects and clinical implications (Estonian Research Council, GMVBS21064PR)
Period: 01.01.2021–31.12.2025
Contact: Professor Maris Laan
E-mail: maris.laan@ut.ee
Read more about the research of the Department of Immunology.
Project: Immune mechanisms in adulthood diabetes (Estonian Research Council, GMVBS0377PR)
Period: 01.01.2020–31.12.2024
Contact: Professor Raivo Uibo
E-mail: raivo.uibo@ut.ee
Project: Human Exposomic Determinants of Immune Mediated Diseases (European Commission Horizon2020, MMVBS20017R)
Period: 01.01.2020–31.12.2024
Contact: professor Raivo Uibo
E-mail: raivo.uibo@ut.ee
Read more about the research of the Department of Pathophysiology.
Project: Integrated model for personalized diabetic retinopathy screening and monitoring using risk-stratification and automated AI-based fundus image analysis (State Education Development Agency (SEDA), MMVBS21381)
Period: 01.05.2021–30.04.2024
Contact: professor Vallo Volke
E-mail: vallo.volke@ut.ee
Project: Staining study to – differentiate organelle originated EV´s from other nanoparticles – via f-NTA (Particle Metrix QUATT) (Particle Metrics GbmH, VMVBS21611)
Period: 28.10.2021–31.08.2023
Contact: Professor Alireza Fazeli
E-mail: alireza.fazeli@ut.ee
Read more about the research of the Department of Anatomy.
Project: Human histology (Institute of the Estonian Language, DMVBS21510)
Period: 16.09.2021–01.09.2024
Contact: Associate Professor Marina Aunapuu
E-mail: marina.aunapuu@ut.ee
Read more about the research of the Department of Microbiology.
Project: conect4children- COllaborative Network for European Clinical Trials For Children (European Commission Horizon2020, MMVBS18106R)
Period: 01.05.2018–30.04.2024
Contact: Professor Irja Lutsar
E-mail: irja.lutsar@ut.ee
Project: Delivering a Unified Research Alliance of Biomedical and public health Laboratories against Epidemics (European Commission, MMVBS23022)
Period: 01.02.2023–31.01.2027
Contact: Professor Irja Lutsar
E-mail: irja.lutsar@ut.ee
Project: Boosting the One Health Research Excellence and Management Capacity of the Estonian University of Life Sciences (European Commission, MMVBS23128R)
Period: 01.01-2023–31.12.2025
Contact: Professor Irja Lutsar
E-mail: irja.lutsar@ut.ee
Project: SARS-coV2 variants Evaluation in pRegnancy and paeDIatrics cohorts (European Commission, MMVBS23269R)
Period: 01.05.2023–31.10.2025
Contact: Professor Irja Lutsar
E-mail: irja.lutsar@ut.ee
Project: GLP1 receptor agonist Liraglutide and NRF2 activator RTA-408 therapy to relieve neurodegenerative symptoms in rat model of Wolfram syndrome (Estonian Research Council, GMVBS20066PS)
Period: 01.01.2020–31.12.2023
Contact: Associate Professor Mario Plaas
E-mail: mario.plaas@ut.ee
Project: Postnatal dysregulation of interneuron development in Wolfram Syndrome: A novel symptom and therapeutic target? (Estonian Research Council, SMVBS22510)
Period: 01.12.2022–30.11.2024
Contact: Associate Professor Mario Plaas
E-mail: mario.plaas@ut.ee
Project: The Role of RNA-recognition Motif of NELFE in Brain Physiology (Estonian Research Council, GMVBS23135J)
Period: 01.03.2023–28.05.2025
Contact: Research Fellow Kadri Seppa
E-mail: kadri.seppa@ut.ee
Project: In vivo safety tests for probiotics (BioCC OÜ, LMVBS22224)
Period: 08.04.2022–31.12.2023
Contact: Associate Professor Mario Plaas
E-mail: mario.plaas@ut.ee
Project: Loss of Wfs1 affects the development and function of GABAergic pathways (TSF) (The Snow Foundation (TSF), MMVBS22562)
Period: 01.07.2022–31.12.2023
Contact: Associate Professor Mario Plaas
E-mail: mario.plaas@ut.ee
