Laboratory of Toxicology


Preclinical efficacy and safety testing of the new investigational drugs



Toxicology group acts as a preclinical contract research organization that provides in vitro and in vivo contract research services, as well as expert consulting services, supporting preclinical drug research and development. We offer a comprehensive package of research services for pharmaceutical industry and biotechnology companies in the preclinical efficacy and safety testing of drug candidates.


Research services

  • Testing of drug candidate on the variety of mouse/rat validated models of neurodegeneration, inflammation, pain, CNS disorders.
  • Human or animal primary neural cultures or cell lines to providing functional analysis of lead compounds in disease-relevant assays.
  • Toxicology testing, ranging from simple acute toxicity studies to complex general toxicity and toxicokinetic studies, prenatal  development  teratology, multi-generation reproduction studies as well as 24-month chronic carcinogenicity studies. Toxicology studies are good laboratory practice (GLP) compliant.
  • Highly-educated scientists provide advice for pharmaceutical product developers on the selection of test protocols, design of experiments, selection of appropriate test systems, data collection, statistical analysis and data interpretation.



  • Professor Aleksandr Žarkovski
  • Associate Professor Külli Jaako 
  • Research Fellow Monika Jürgenson 
  • Research Fellow Kaili Anier 
  • Research Fellow Janeli Viil