Laboratory of Toxicology

Preclinical efficacy and safety testing of the new investigational drugs

Goal

Toxicology group acts as a preclinical contract research organization that provides in vitro and in vivo contract research services, as well as expert consulting services, supporting preclinical drug research and development. We offer a comprehensive package of research services for pharmaceutical industry and biotechnology companies in the preclinical efficacy and safety testing of drug candidates.

Research services

• Testing of drug candidate on the variety of mouse/rat validated models of neurodegeneration, inflammation, pain, CNS disorders.
• Human or animal primary neural cultures or cell lines to providing functional analysis of lead compounds in disease-relevant assays.
• Toxicology testing, ranging from simple acute toxicity studies to complex general toxicity and toxicokinetic studies, prenatal  development  teratology, multi-generation reproduction studies as well as 24-month chronic carcinogenicity studies. Toxicology studies are good laboratory practice (GLP) compliant.
• Highly-educated scientists provide advice for pharmaceutical product developers on the selection of test protocols, design of experiments, selection of appropriate test systems, data collection, statistical analysis and data interpretation.

People

• Professor Aleksandr Žarkovski
• Associate Professor Külli Jaako 
• Research Fellow Monika Jürgenson 
• Research Fellow Kaili Anier 
• Research Fellow Janeli Viil