Laboratory of Precision and Nanomedicine

 

The research focus of the Laboratory of Precision and Nanomedicine is to develop smart cancer therapeutics with increased potency and decreased side effects. We use peptide phage display screens to identify homing peptides that bind to specific targets in the vasculature. Corresponding synthetic peptides are explored for targeting low molecular weight drugs, biologicals and nanoparticle drugs into tumors to increase their therapeutic index. Our scope includes understanding the molecular interactions that drive specificity and activity, focusing on Tumor Penetrating Peptides that trigger bulk extravascular transport in the tumor tissue. The work in the Laboratory of Precision and Nanomedicine is carried out in close collaboration with the laboratories of Drs. E. Ruoslahti and K.N. Sugahara at the Sanford-Burnham Medical Research Institute in La Jolla, California.

Laboratory of Precision and Nanomedicine is supported by EMBO Installation Grant, Wellcome Trust Senior Research Fellowship, and European Research Council Starting Grant.

Research

Publications and patents

Doctoral theses

Portree akadeemik Pärt Petersonist

Pärt Peterson was elected as member of the Academy of Sciences in biomedicine

Töö viirusega laboris

Vaccine created by University of Tartu researchers to prevent a dangerous tropical disease received approval

Doctoral defence: Ling Yan "Stress-associated immune mechanisms of schizophrenia: the importance of region-specific microglia-neurovascular interaction"

On December 15th Ling Yan will defend a thesis "Stress-associated immune mechanisms of schizophrenia: the importance of region-specific microglia-neurovascular interaction".