Doctoral theses of the Department of Physiology

Marite Punapart, (sup) Mario Plaas, Anton Terasmaa, Eero Vasar. Effects of Valproate and Liraglutide in Rodent Models of Wolfram Syndrome: Emphasis on Transcriptomic Changes in the Renin-Angiotensin-Aldosterone System. University of Tartu, Faculty of Medicine.
Fangling Xuan, 2024 (sup) Li Tian; Eero Vasar, Kersti Lilleväli, Claudio Rivera Baeza. Regulation of stress response in first episode schizophrenia by monocytes and microglia. University of Tartu, Faculty of Medicine.
Ling Yan, 2023, (sup) Li Tian, Eero Vasar, Cai Song. Molecular and functional heterogeneity of microglia and the modulatory effects of n-3 polyunsaturated fatty acids in mouse depression-like behaviors. University of Tartu, Faculty of Medicine.
Taavi Vanaveski, 2023, (sup) Mari-Anne Philips, Eero Vasar, Kersti Lilleväli, Dan Lindholm. Modeling the quantitative nature of neuropsychiatric disorders in animal models: metabolic, behavioral and genetic profiles. University of Tartu, Faculty of Medicine.
Maria Piirsalu, 2023, (sup) Kersti Lilleväli, Eero Vasar, Mihkel Zilmer. Effects of inflammation and diet on the metabolic profile and selected genetic parameters of Bl6 and 129Sv mouse lines. University of Tartu, Faculty of Medicine.
Maria Kaare, 2023, (sup) Mari-Anne Philips, Eero Vasar, Este Leidmaa. The involvement of NEGR1 and LSAMP in the psychiatric disorders is mediated through monoaminergic neurotransmission and changes in the systemic metabolism. University of Tartu, Faculty of Medicine.
Jane Varul, 2023, (sup) Eero Vasar, Mari-Anne Philips, Jürgen Innos. Different stress coping strategies of 129Sv and C57/Bl6 mouse strains - evidence from behavioural, pharmacological, metabolomics and gene expression studies. University of Tartu, Faculty of Medicine.
Aleksandr Bregin, 2022, (sup) Mari-Anne Philips, Eero Vasar, Jürgen Innos. Alterations of emotional behaviour induced by the genetic invalidation of the limbic system associated membrane protein (Lsamp) – potential implications for neuropsychiatric disorders. University of Tartu, Faculty of Medicine.
Kadri Seppa, 2021, (sup) Mario Plaas, Eero Vasar, Anton Terasmaa. The neuroprotective effect of GLP-1 receptor agonist liraglutide in a rat model of Wolfram syndrome. University of Tartu, Faculty of Medicine.
Liisa Leppik, 2021, (sup) Liina Haring, Eero Vasar, Mihkel Zilmer. Alterations in metabolomic profile of lipids, amino acids and biogenic amines in the early course of schizophrenia spectrum disorders. University of Tartu, Faculty of Medicine.
Roman Balõtšev, 2020, (sup) Liina Haring, Mihkel Zilmer, Eero Vasar, Kati Koido. Interaction between the immune and metabolic systems in different stages of schizophrenia spectrum disorders. University of Tartu, Faculty of Medicine.
Hardo Lilleväli, 2020, (sup) Katrin Õunap, Kersti Lilleväli. Hyperphenylalaninaemias and neurophysiological disorders associated with the condition. University of Tartu, Faculty of Medicine.
Kattri-Liis Eskla, 2019, (sup) Hendrik Luuk, Eero Vasar, Christian Ansgar Hundahl. Therapeutic strategies for ischemia reperfusion injury. University of Tartu, Faculty of Medicine.
Katyayani Singh, 2019, (sup) Mari-Anne Philips, Eero Vasar, Kersti Lilleväli. Neuropsychiatric endophenotypes - focusing on IgLON adhesion molecules in the mouse brain. University of Tartu, Faculty of Medicine.
Maarja Toots, 2018, (sup) Eero Vasar, Mario Plaas. Pharmacological challenge in rodent models of Wolfram syndrome with emphasis on diabetic phenotype. University of Tartu, Faculty of Medicine.
Alina Altpere, 2018, (sup) Silva Sütt, Sirli Raud, Eero Vasar. Targeting of mechanisms of elevated anxiety in female Wfs1-deficient mice. University of Tartu, Faculty of Medicine.
Triin Tekko, 2018, (sup) Kersti Lilleväli, Mari-Anne Philips, Eero Vasar. Neurodevelopmental approach in the study of the function of Wfs1 and Lsamp , potential targets in the regulation of emotional behaviour. University of Tartu, Faculty of Medicine.
Kärt Kriisa, 2018, (sup) Liina Haring, Mihkel Zilmer, Eero Vasar. Profile of acylcarnitines, inflammation and oxidative stress in first-episode psychosis before and after antipsychotic treatment. University of Tartu, Faculty of Medicine.
Liina Haring, 2017, (sup) Rene Mõttus, Eduard Maron, Aleksandr Žarkovski. Cognitive functioning after first psychotic episode. University of Tartu, Faculty of Medicine.
Indrek Heinla, 2016, (sup) Eero Vasar, Mari-Anne Philips. Behavioural and genetic comparison of B6 and 129Sv mouse lines focusing on the anxiety profile and the expression of Lsamp gene. University of Tartu, Faculty of Medicine.
Tanel Visnapuu, 2015, (sup) Eero Vasar, Hendrik Luuk. Pharmacological and behavioral characterization of the monoaminergic and GABA-ergic systems of Wfs1-deficient mice. University of Tartu, Faculty of Medicine.
Paula Reemann, 2015, (sup) Külli Kingo, Viljar Jaks, Sulev Kõks, Olavi Vasar. The effects of microenvironment on skin cells. University of Tartu, Faculty of Medicine.
Sten Ilmjärv, 2015, (sup) Jaak Vilo, Eero Vasar, Hendrik Luuk. Estimating differential expression from multiple indicators. University of Tartu, Faculty of Medicine.
Jürgen Innos, 2013, (sup) Eero Vasar, Sulev Kõks. Behavioural, pharmacological and neurochemical characterisation of limbic system-associated membrane protein (LSAMP) deficient mice. University of Tartu, Faculty of Medicine.
Mario Plaas, 2013, (sup) Sulev Kõks, Alar Karis, Eero Vasar. Animal model of Wolfram Syndrome in mice: behavioural, biochemical and psychopharmacological characterization. University of Tartu, Faculty of Science and Technology.
Ene Reimann, 2012, (sup) Külli Kingo, Sulev Kõks. Description of the cytokines and cutaneous neuroendocrine system in the development of vitiligo. University of Tartu, Faculty of Medicine.
Kertu Rünkorg, 2012, (sup) Eero Vasar, Vallo Volke. Functional changes of dopamine, endopioid and endocannabinoid systems in CCK2 receptor deficient mice. University of Tartu, Faculty of Medicine.
Tiit Salum, 2011, (sup) Mihkel Zilmer, Eero Vasar. Similarity and difference of temperature-dependence of the brain sodium pump in normal, different neuropathological, and aberrant conditions and its possible reasons. University of Tartu, Faculty of Medicine.
Ranno Rätsep, 2010, (sup) Eero Vasar, Külli Kingo, Sulev Kõks, Helgi Silm. Genetics of psoriasis and vitiligo, focus on family IL10 cytokines. University of Tartu, Faculty of Medicine.
Mari-Anne Philips, 2010, (sup) Eero Vasar, Sulev Kõks. Characterizarion of Myg1 Gene and Protein: Expression Patterns, Subcellular Localization, Gene Deficient Mouse and Functional Polymorphismis in Human. University of Tartu, Faculty of Medicine.
Silva Sütt, 2010, (sup) Eero Vasar, Sulev Kõks. Role of Endocannabinoid System and Wfs1 in Regulation of Emotional Behaviour: Behavioural, Pharmacological and Genetic Studies. University of Tartu, Faculty of Medicine.
Kaido Kurrikoff, 2009, (sup) Eero Vasar, Sulev Kõks. Involvement of cholecystokinin in chronic pain mechanisms and endogenous antinociception (Koletsüstokiniini seotus kroonilise valu mehhanismidega ja endogeense valuvastase süsteemiga). University of Tartu, Faculty of Medicine.
Anne Must, 2009, (sup) Eero Vasar, Aavo Lang, Sulev Kõks. Studies on Molecular Genetics of Male Completed Suicide in Estonian Population. University of Tartu, Faculty of Medicine.
Hendrik Luuk, 2009, (sup) Eero Vasar, Sulev Kõks. Distribution and behavioral effects of WFS1 protein in the central nervous system. University of Tartu, Faculty of Medicine.
Urho Abramov, 2008, (sup) Eero Vasar Sex and environmental factors determine the behavioural phenotype of mice lacking CCK2 receptors: implications for the behavioural studies in transgenic lines. University of Tartu, Faculty of Medicine.
Aleksei Nelovkov, 2006, (sup) Eero Vasar, Sulev Kõks. Behavioural and neurogenetic study of molecular mechanisms involved in regulation of exploratory behaviour in rodents. University of Tartu, Faculty of Medicine.
Tarmo Areda, 2006, (sup) Sulev Kõks, Toomas Asser, Alar Karis. Behavioural and neurogenetic study of mechanisms related to cat odour induced anxiety in rodents. University of Tartu, Faculty of Medicine.
Vootele Võikar, 2006, (sup) Eero Vasar, Heikki Rauvala. Evaluation of Methods and Applications for Behavioural Profiling of Transgenic Mice. University of Helsinki.
Külli Kingo, 2005, (sup) Eero Vasar, Helgi Silm, Sulev Kõks. The interleukin-10 family cytokines gene polymorphisms in plaque psoriasis. University of Tartu, Faculty of Medicine.
Kati Koido, 2005, (sup) Sulev Kõks, Andres Metspalu. Singlenucleotide polymorphism profiling of 22 candidate genes in mood and anxiety disorders. University of Tartu, Faculty of Medicine.
Sirli Raud, 2005, (sup) Eero Vasar, Vallo Volke, Sulev Kõks. Cholecystokinin 2 receptor deficient mice: changes in function of GABA-ergic system. University of Tartu, Faculty of Medicine.
Alar Veraksitš, 2003, (sup) Jaak Maaroos, Eero Vasar. Characterization of behavioural and biochemical phenotype of cholecystokinin-2 receptor deficient mice: changes in the function of the dopamine- and endopioidergic system. University of Tartu, Faculty of Medicine.
Sulev Kõks, 1999, (sup) Eero Vasar. Cholecystokinin (CCK) - induced anxiety in rats: influence of environmental stimuli and involvement of endopioid mechanisms and serotonin. University of Tartu, Faculty of Biology and Geography.
Vallo Volke, 1999, (sup) Eero Vasar. Pharmacological and biochemical studies on nitric oxide in the regulation of behaviour. University of Tartu, Faculty of Medicine.
Aavo Lang, 1995, (sup) Eero Vasar. The role of dopamine, 5-hydroxytryptamine, sigma and NMDA receptors in the action of antipsychotic drugs. University of Tartu, Faculty of Medicine.
Jaanus Harro, 1990, (sup) Lembit Allikmets, Eero Vasar. On the role of cholecystokinin and benzodiazepine receptors in the mechanism of action of anxiogenic and anxiolytic drugs. University of Tartu, Faculty of Medicine.
Andres Soosaar, 1989, (sup) Eero Vasar, Lembit Allikmets. The role of the brain cholecystokinin(CCK-8)-ergic mechanisms in the regulation of behaviour and in the action of antipsychotic drugs. University of Tartu, Faculty of Medicine.